Custom Research Design

Custom Research Design

As broad genomic profiling technologies have enabled researchers to identify thousands of potential markers of interest in plants, animals and humans, a new technology is needed for subsequent low density analysis and validation of the truly relevant markers.

As an alternative to traditional methods for fine mapping and validation of genome-wide analysis, the NGG provides a flexible and cost-effective approach to biomarker interrogation in plant, animal and clinical research. The assay can be designed to survey a broad range of mutations (including SNPs, CNVs, methylation events and InDels) and multiple questions can be asked within a single experiment. The NGG provides an economical platform for rapid assessment of biomarkers, enabling hundreds of markers for hundreds to thousands of samples to be queried in parallel using a single lane of a NGS flow cell.

The flexibility of the design platform allows researchers to quickly and easily build any genotyping panel and we at Eureka Genomics are always seeking partners for commercial development. Come to us with your research needs and ideas and, if appropriate, EG can help commercialize your ideas, helping to generate ongoing revenue for your research institution. Of course, for projects where confidentiality is of utmost concern, we are happy to work with you on an exclusive basis for proprietary markers.

Learn more about partnering with Eureka Genomics

Technology

Eureka Genomics’ next-gen genotyping (NGG) provide an improved and economical alternative to traditional technologies for profiling hundreds of SNPs (or other genetic markers) in hundreds to thousands of samples using Next Generation Sequencing (NGS). The assay can be broadly applied to the detection of SNPs, InDels, CNV and methylation and is compatible with DNA or RNA from virtually any organism, even when genome information may be incomplete. The NGG provides rapid, accurate, cost-effective answers by combining discriminatory power of hybridization and ligation, focused high throughput sequencing and rigorously designed statistical analysis.

Eureka Genomics offers access to NGG as either standard or custom designed panels and testing can be performed either as a service through our expert scientific team or in your own lab (with technical support from EG to get you started). The assay is sequencing instrument agnostic, so regardless of the platform you have invested resources into or upgrade to in the future the NGG can be adapted to ensure easy assimilation and rapid data generation for your research or clinical goals. And because NGS is used to provide focused information on only the sequences of interest (and not the rest of the genome), the cost per genotype is extremely low.

NGG Benefits

Platform Agnostic

Compatible with your existing sequencing platform rather than requiring investment in expensive, dedicated workflows.

Flexible Design

Interrogate all of your SNPs of interest in a single assay rather coverage than buying limited, fixed panels or paying premiums for custom assay design.

Faster Answers

Query hundreds of SNPs for hundreds to thousands of samples in parallel rather than one sample at a time.

Build Efficiency

Ask multiple biological questions simultaneously in a single sequencing lane to reduce wasted space.

Reduce Cost

Significantly reduce the price per genotype of custom panel development compared to alternative technologies.

Evolve with Eureka

Leverage the future of NGS-based genetic testing with a technology that will easily adapt to your instrumentation upgrades or conversions.

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